Tam sim no, feem ntau cov lag luam siv phaj thiab thav duab, centrifugation thiab lwm txoj hauv kev kom tshem tawm cov kab mob thiab qee qhov macromolecular impurities hauv fermentation broth.Cov kua dej sib cais nyob rau hauv txoj kev no muaj cov ntsiab lus siab ntawm cov dej tsis huv, cov kua dej loj loj, thiab cov kua dej tsis txaus, uas ua rau muaj kev ua haujlwm tsis zoo ntawm cov txheej txheem purification xws li resin lossis extraction hauv cov txheej txheem tom ntej, uas ua rau cov nqi ntau lawm."Bona Bio" tau ua tiav cov txheej txheem kev sib cais ntawm daim nyias nyias mus rau cov txheej txheem ntawm kev tshem tawm impurity thiab purification ntawm fermentation broth, ua tiav cov teeb meem ntawm kev sib cais, purification thiab concentration nyob rau hauv industrialized zus tau tej cov fermentation broth, thiab tib lub sij hawm ua tiav lub hom phiaj ntawm lub zog. kev txuag, txo kev noj thiab ua kom huv si.Nws muab kev lag luam, qib siab thiab tsim nyog cov kev daws teeb meem rau cov lag luam fermentation.
Bona membrane sib cais tshuab zoo:
1. Lub siab precision ntawm daim nyias nyias ua kom paub meej cov nyhuv ntawm cov kua roj ntsha fermentation kua, uas muaj qhov zoo zoo piv nrog cov txheej txheem ib txwm muaj, qhov kev tshem tawm impurity yog tag nrho, thiab cov khoom zoo yog pom tseeb txhim kho.
2. Membrane filtration yog nqa tawm nyob rau hauv ib qho chaw kaw, nrog ib tug high degree ntawm automation, thiab cov txheej txheem filtration txo cov pov tseg ntawm fermentation broth thiab kuab paug rau cov khoom.
3. Cov txheej txheem membrane pom tuaj yeem ua haujlwm ntawm qhov kub thiab txias (25 ° C), tsis muaj theem hloov, hloov tau zoo, tsis muaj tshuaj lom neeg, tsis muaj kev puas tsuaj rau cov khoom xyaw, tsis muaj kev puas tsuaj rau cov khoom siv hluav taws xob, thiab txo qis zog noj.
4. Membrane filtration txheej txheem, lub mycelium tuaj yeem rov qab tau thaum qhia meej, tshem tawm cov impurities, tsom thiab purifying cov khoom;
5. Cov khoom siv membrane concentration muaj cov flux loj, ceev concentration ceev, thiab cov txheej txheem ruaj khov thiab txhim khu kev qha;
6. Membrane concentration muaj siab filtration precision, thiab cov kua lim dej muaj siab purity.Nws tuaj yeem raug txiav txim siab rov siv dua hauv kev tsim khoom, uas txo cov dej phwj tuaj thiab muaj kev tiv thaiv ib puag ncig zoo;
7. Lub degree ntawm automation yog siab, muaj kev nyab xeeb thiab txhim khu kev qha, txo cov kev siv zog ua haujlwm, thiab cov txheej txheem membrane pom yog nqa tawm hauv lub thawv kaw kom ua tiav cov khoom huv si;
8. Cov khoom siv membrane muaj qhov ntim loj thiab thaj chaw me me, uas yooj yim rau kev hloov pauv, nthuav tawm lossis cov haujlwm tshiab ntawm cov chaw qub qub, uas tuaj yeem txo cov nqi tsim khoom thiab peev.
Tam sim no, tus editor ntawm Shandong Bona Group yuav qhia txog daim ntawv thov ntawm daim nyias nyias nyias tshuab nyob rau hauv lom fermentation broth.
1. Kev siv tshuaj tua kab mob tom qab kho
Muaj cov khoom lag luam, cov khoom seem nruab nrab thiab cov protein uas muaj nyob hauv cov tshuaj penicillin fermentation filtrate, uas yuav ua rau emulsification thaum lub sij hawm rho tawm.Nws yog ib qho nyuaj rau cais cov aqueous theem thiab ester theem, uas cuam tshuam rau kev hloov ntawm penicillin ntawm ob theem, ncua lub sij hawm extraction txheej txheem, thiab txo cov concentration ntawm penicillin nyob rau hauv lub extraction seem thiab yield.Kev kho mob ntawm penicillin fermentation broth nrog ultrafiltration membrane tuaj yeem tshem tawm cov protein thiab lwm yam macromolecular impurities thiab tshem tawm emulsification thaum lub sij hawm rho tawm.Tom qab ultrafiltration, tag nrho cov soluble proteins tau khaws cia, thiab tag nrho cov txiaj ntsig ntawm ultrafiltration thiab extraction ntawm penicillin yog qhov pib zoo ib yam li cov txiaj ntsig qub extraction, thiab theem kev sib cais yog ib qho yooj yim kom ua tiav thaum lub sij hawm rho tawm, uas txo qhov hnyav poob, tsis tas yuav ntxiv demulsifier. , thiab txo cov nqi.
2. Daim ntawv thov tom qab ua cov vitamins
Vitamin C yog ib yam khoom vitamin uas tsim los ntawm fermentation.Ntau qhov kev tshawb fawb tau ua tiav ntawm kev kho Vc fermentation broth nrog membrane technology, thiab industrialization tau ua tiav tiav lawm.Vc yog fermented los ntawm sorbitol nyob rau hauv qhov kev txiav txim ntawm cov kab mob los tsim cov nruab nrab gulonic acid, uas yog ntxiv hloov thiab ua tom qab purification.Gulonic acid fermentation broth yog pretreated kom tshem tawm cov khoom impurities thiab ib co proteins, thiab ces ultrafiltration tshem tawm macromolecular impurities xws li cov proteins thiab polysaccharides, purifying cov kua pub nkag mus rau cov kauj ruam tom ntej ntawm ion txauv, nce tus nqi pauv ntawm ion txauv kem thiab txo. lub regeneration kua thiab ntxuav dej siv, yog li txo cov txheej txheem ion pauv ib-kauj ruam thiab txuag lub zog.Yog tias kho nrog rov qab osmosis daim nyias nyias, feem ntau ntawm cov dej hauv cov khoom siv raw tuaj yeem raug tshem tawm, tsis yog thawj theem concentration thiab evaporation txheej txheem hauv kev tsim khoom.Kev siv cov txheej txheem membrane shortens cov txheej txheem ntawm proto-gulonic acid extraction, txo cov kua qaub-base regeneration pov tseg kua thiab ntxuav dej, thiab txo cov thermal decomposition poob ntawm gulonic acid thaum lub sij hawm concentration, txo cov nqi ntau lawm.
3. Daim ntawv thov hauv amino acid tom qab ua tiav
Monosodium glutamate wastewater belongs rau high-concentration refractory organic khib nyiab, uas tsis tsuas yog muaj cov organic ntsiab lus, tab sis kuj muaj siab NH4 + thiab SO4 ^ 2-.Nws yog ib qho nyuaj rau ib txwm siv tshuaj lom neeg kev kho mob kom ua tau raws li tus qauv tso tawm.Ultrafiltration membrane yog siv los tshem tawm cov kab mob thiab cov kab mob hauv cov dej khib nyiab monosodium glutamate.Macromolecular protein thiab lwm yam khoom, qhov kev tshem tawm ntawm SS hauv cov dej khib nyiab tuaj yeem ncav cuag ntau dua 99%, thiab qhov kev tshem tawm ntawm CODcr yog kwv yees li 30%, uas tuaj yeem txo qhov kev ua haujlwm ntawm cov txheej txheem lom neeg thiab rov qab tau cov protein hauv cov dej khib nyiab.
Membrane sib cais tshuab muaj qhov zoo ntawm cov khoom siv yooj yim, kev ua haujlwm yooj yim, kev ua haujlwm siab thiab txuag hluav taws xob, thiab tau siv dav hauv ntau yam.Nrog rau kev nce qib ntawm kev tshawb fawb thiab thev naus laus zis, cov tshuab sib cais membrane yuav raug txhim kho tas li thiab siv rau ntau qhov kev lag luam.
Lub sij hawm xa tuaj: Plaub Hlis-20-2022